Abstract
We describe an electrochemical analog of fluorescence polarization that supports the quantitative measurement of a specific protein, the chemokine IP-10, directly in undiluted blood serum. The sensor is label-free, wash-free, and electronic, suggesting it could support point-of-care detection of diagnostic proteins in largely unprocessed clinical samples.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Biomarkers / blood
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Chemokine CXCL10 / analysis*
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Chemokine CXCL10 / blood
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DNA / chemistry*
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DNA / metabolism
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Electrochemical Techniques / methods*
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Humans
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Protein Structure, Secondary
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Serum / chemistry*
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Serum / metabolism
Substances
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Biomarkers
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CXCL10 protein, human
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Chemokine CXCL10
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DNA