Patients with penile cancer and the risk of (pre)malignant cervical lesions in female partners: a retrospective cohort analysis

BJU Int. 2013 Nov;112(7):905-8. doi: 10.1111/bju.12237. Epub 2013 Jul 26.

Abstract

Objective: To determine if female partners of patients with penile cancer have more cervical lesions and neoplasia than would be expected from population-based data.

Patients and methods: We included all consecutive patients with primary penile carcinoma in the period 2004-2010. Results of Dutch cervical cancer screening were used to consider (pre)malignant cervical lesions in female partners of patients with penile cancer.

Results: In all, 206 women were included. Gynaecological information was available in 195 women: Papanicolaou test (PAP) smears were normal were in 129 partners, 10 smears were abnormal (5.1%, 95% confidence interval 2.5-9.2). PAP2 was found in five, PAP3a in two, PAP3b in two women and PAP4 in one woman. Colposcopy in two women with PAP3b showed cervical intraepithelial neoplasia grade 3 in both. This prevalence was not different from baseline results in the general Dutch population.

Conclusion: Female partners of patients with penile cancer did not show more premalignant cervical lesions than in the general population.

Keywords: human papilloma virus; penile neoplasms; uterine cervical neoplasms.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cohort Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Penile Neoplasms*
  • Precancerous Conditions / epidemiology*
  • Precancerous Conditions / pathology*
  • Retrospective Studies
  • Risk Factors
  • Sexual Partners*
  • Uterine Cervical Neoplasms / epidemiology*
  • Uterine Cervical Neoplasms / pathology*