Changing aetiology of hand, foot and mouth disease in Linyi, China, 2009-2011

Clin Microbiol Infect. 2014 Jan;20(1):O47-9. doi: 10.1111/1469-0691.12301. Epub 2013 Aug 1.

Abstract

Millions of hand, foot and mouth disease cases occur annually and the disease is considered a significant public health threat in China. We have focused on Linyi for 3 years to analyse the aetiological spectrum and epidemic changes. The reported number of cases of HFMD in Linyi declined in 2011,with the percentage of HEV71 dropping to 11%. Although CVA16 rose to 51% in 2011, the number of CVA16 cases did not change significantly compared with the previous 2 years. Other types of enteroviruses were detected in 2011 and might play more important roles in future epidemics.

Keywords: Hand, foot and mouth disease; Human enterovirus 71; Human enteroviruses; coxsackie virus A16; molecular epidemiology.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child, Preschool
  • China / epidemiology
  • Disease Outbreaks
  • Enterovirus A, Human / genetics
  • Enterovirus A, Human / isolation & purification*
  • Enterovirus B, Human / genetics
  • Enterovirus B, Human / isolation & purification*
  • Evolution, Molecular
  • Genes, Viral
  • Hand, Foot and Mouth Disease / epidemiology*
  • Hand, Foot and Mouth Disease / virology*
  • Humans
  • Infant
  • Molecular Sequence Data
  • Pharynx / virology*
  • Phylogeny
  • Polymerase Chain Reaction

Associated data

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