PharmGKB summary: cyclosporine and tacrolimus pathways

Pharmacogenet Genomics. 2013 Oct;23(10):563-85. doi: 10.1097/FPC.0b013e328364db84.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • ATP Binding Cassette Transporter, Subfamily B
  • ATP Binding Cassette Transporter, Subfamily B, Member 1 / genetics
  • Calcineurin / genetics
  • Calcineurin / metabolism
  • Cyclosporine* / pharmacokinetics
  • Cyclosporine* / pharmacology
  • Cyclosporine* / therapeutic use
  • Cytochrome P-450 CYP3A / genetics
  • Genetic Variation
  • Graft Rejection / drug therapy*
  • Graft Rejection / prevention & control*
  • Humans
  • Immunosuppressive Agents* / pharmacokinetics
  • Immunosuppressive Agents* / pharmacology
  • Immunosuppressive Agents* / therapeutic use
  • MAP Kinase Signaling System
  • Organ Transplantation
  • Pharmacogenetics
  • Polymorphism, Genetic
  • Tacrolimus* / pharmacokinetics
  • Tacrolimus* / pharmacology
  • Tacrolimus* / therapeutic use
  • Transforming Growth Factor beta1 / genetics

Substances

  • ABCB1 protein, human
  • ATP Binding Cassette Transporter, Subfamily B
  • ATP Binding Cassette Transporter, Subfamily B, Member 1
  • Immunosuppressive Agents
  • TGFB1 protein, human
  • Transforming Growth Factor beta1
  • Cyclosporine
  • CYP3A5 protein, human
  • Cytochrome P-450 CYP3A
  • CYP3A4 protein, human
  • Calcineurin
  • Tacrolimus