Activation of promutagens by human cDNA-expressed cytochrome P450s

Prog Clin Biol Res. 1990:340B:77-86.

Authors

F J Gonzalez¹, T Aoyama, H V Gelboin

Affiliation

¹ Laboratory of Molecular Carcinogenesis, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.

PMID: 2392453

No abstract available

MeSH terms

Amines / metabolism
Biotransformation
Carcinogens / metabolism
Cytochrome P-450 Enzyme System / genetics
Cytochrome P-450 Enzyme System / metabolism*
DNA / genetics
Genetic Vectors
Humans
Mutagens / metabolism*
Recombinant Fusion Proteins / metabolism
Vaccinia virus / genetics

Substances

Amines
Carcinogens
Mutagens
Recombinant Fusion Proteins
DNA
Cytochrome P-450 Enzyme System