A study was made to determine how prevalent oral and oropharyngeal cancer proved to be in 600 E.N.T. out-patients upon their initial examination. The aim was to ascertain which population was at high risk for thys type cancer through the use of computerized analysis of the risk factors. By scoring risk factors for oral and oropharyngeal cancer, subjects were classified into 3 risk classes: low, medium and high. Endoscopy proved positive in 22 cases only in the high risk class. Further diagnostic procedures, performed for all subjects, revealed 16 cases of squamous cell carcinoma, 1 'in situ' carcinoma, and 5 precancerous lesions of the oral cavity and oropharynx. This data is then discussed and the suggestion made that scoring such risk factors as tobacco and alcohol consumption could also be effective in identifying the high risk groups for this disease in a selective screening program.