Abstract
We describe 3 children who developed teeth and tongue discoloration while receiving intravenous linezolid for 2 to 3 weeks. Linezolid was coadministered with piperacillin-tazobactam or meropenem. Teeth and tongue discoloration was reversible with dental cleaning after discontinuation of linezolid. We review the published pediatric and adult cases regarding teeth and tongue discoloration after linezolid administration.
MeSH terms
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Acetamides / adverse effects*
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Acetamides / therapeutic use
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Adolescent
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Anti-Infective Agents / adverse effects*
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Anti-Infective Agents / therapeutic use
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Bacterial Infections / drug therapy
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Child
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Child, Preschool
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Female
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Hospitalization
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Humans
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Linezolid
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Male
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Oxazolidinones / adverse effects*
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Oxazolidinones / therapeutic use
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Tongue / drug effects*
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Tongue / pathology
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Tooth Discoloration / chemically induced*
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Tooth Discoloration / pathology
Substances
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Acetamides
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Anti-Infective Agents
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Oxazolidinones
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Linezolid