[Large cell calcifying Sertoli cell tumour: A case report]

Ann Pathol. 2013 Aug;33(4):270-2. doi: 10.1016/j.annpat.2013.03.001. Epub 2013 May 23.
[Article in French]

Abstract

A 19-year-old male Caucasian, without prior medical history, noticed a painless right testicular mass. Physical examination revealed neither gynecomastia nor abnormal skin pigmentation. Serum alpha-fetoprotein, β-HCG and testosterone levels were normal. Sonography depicted an intratesticular diffusely hyperechoic lesion with acoustic shadowing. The patient underwent right orchiectomy. Histology revealed a benign large cell calcifying Sertoli cell tumour. This tumour is rare and may be associated with genetic abnormalities.

Keywords: Carney complex; Complexe de Carney; Large cell calcifying sertoli cell tumour; Peutz-Jeghers syndrome; Syndrome de Peutz-Jeghers; Tumeurs à cellules de Sertoli à grandes cellules calcifiantes.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenoma / diagnosis
  • Biomarkers, Tumor
  • Calbindin 2 / analysis
  • Calcinosis / diagnosis
  • Calcinosis / diagnostic imaging
  • Calcinosis / pathology*
  • Calcinosis / surgery
  • Diagnosis, Differential
  • Humans
  • MART-1 Antigen / analysis
  • Male
  • Orchiectomy
  • Sertoli Cell Tumor / chemistry
  • Sertoli Cell Tumor / diagnosis
  • Sertoli Cell Tumor / diagnostic imaging
  • Sertoli Cell Tumor / pathology*
  • Sertoli Cell Tumor / surgery
  • Testicular Neoplasms / chemistry
  • Testicular Neoplasms / diagnosis
  • Testicular Neoplasms / diagnostic imaging
  • Testicular Neoplasms / pathology*
  • Testicular Neoplasms / surgery
  • Ultrasonography
  • Vimentin / analysis
  • Young Adult

Substances

  • Biomarkers, Tumor
  • CALB2 protein, human
  • Calbindin 2
  • MART-1 Antigen
  • MLANA protein, human
  • Vimentin