[Complete remission by sorafenib for local reccurence of renal cell carcinoma with a tempraly elevation of C-reactive protein: a case report]

Atsushi Yoshinaga; Nobutaka Ichiyanagi; Shigeyoshi Kamata

doi:10.5980/jpnjurol.104.609

[Complete remission by sorafenib for local reccurence of renal cell carcinoma with a tempraly elevation of C-reactive protein: a case report]

Nihon Hinyokika Gakkai Zasshi. 2013 Jul;104(4):609-11. doi: 10.5980/jpnjurol.104.609.

[Article in Japanese]

Authors

Atsushi Yoshinaga¹, Nobutaka Ichiyanagi, Shigeyoshi Kamata

Affiliation

¹ Department of Urology, Souka Municipal Hospital.

PMID: 23971370
DOI: 10.5980/jpnjurol.104.609

Abstract

A 66-year-old man appeared with a local recurrence of RCC 9 months after nephrectomy (clear cell carcinoma > sarcomatoid carcinoma, G2 > 3, pT3a). A tempraly elevation of serum C-reactive protein (CRP) appeared on administration of sorafenib and decrease of vascularity of the tumor was found on CT. After 13 months of sorafenib administration the recurrent tumor disappeared completely and serum CRP was normalized concomitantly. He currently remains in complete remission for 37 months.

Publication types

Case Reports

MeSH terms

Aged
Antineoplastic Agents / therapeutic use*
C-Reactive Protein / analysis*
Carcinoma, Renal Cell / blood
Carcinoma, Renal Cell / drug therapy*
Humans
Kidney Neoplasms / blood
Kidney Neoplasms / drug therapy*
Male
Neoplasm Recurrence, Local
Niacinamide / analogs & derivatives*
Niacinamide / therapeutic use
Phenylurea Compounds / therapeutic use*
Remission Induction
Sorafenib

Substances

Antineoplastic Agents
Phenylurea Compounds
Niacinamide
C-Reactive Protein
Sorafenib