The costs of mobilisation and collection of peripheral blood stem cells in multiple myeloma and lymphoma in an European country: results from The Gruppo Italiano Trapianto Midollo Osseo (GITMO) and Società Italiana di Emaferesi e Manipolazione Cellulare (SIdEM) survey

Transfus Apher Sci. 2013 Dec;49(3):615-22. doi: 10.1016/j.transci.2013.07.025. Epub 2013 Aug 6.

Abstract

Scarce information is available about the cost of mobilisation/collection of peripheral blood stem cells for patients undergoing autologous transplant for relapsed Lymphoma or Multiple Myeloma. This paper reports the consumption of resources and costs collected through a survey among Italian Centres who adhere to the GITMO and SIdEM scientific societies. General transplant information was extracted from the European Promise database. Resources used alongside the phases of mobilisation/collection were retrieved. Resources for each of the process phases were quantified and averaged across centres and a unit cost value was attributed, based on administrative data from 3 centres, tariffs and market values. 25/89 Centres (34% of 2009 Promise transplants) provided data according to their standard practice. The mean cost/patient of the process of cell mobilisation/collection was € 6830 ± 1802 for Multiple Myeloma and € 7304 ± 1542 for Lymphoma. The organisational path for PBSC mobilisation/collection appears complex and cumbersome, spread amongst different treatment settings, with many different healthcare professionals being involved and considerable amounts of time and resources being currently dedicated to the management of patients requiring autologous transplantation.

Keywords: Apheresis; Cost; Hematopoietic transplantation; Lymphoma; Myeloma.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Data Collection
  • European Union
  • Female
  • Health Care Costs
  • Hematopoietic Stem Cell Mobilization / economics*
  • Hematopoietic Stem Cell Mobilization / methods
  • Hematopoietic Stem Cell Transplantation / economics*
  • Hematopoietic Stem Cell Transplantation / methods
  • Humans
  • Italy
  • Lymphoma / economics
  • Lymphoma / surgery*
  • Male
  • Middle Aged
  • Multiple Myeloma / economics
  • Multiple Myeloma / surgery*
  • Peripheral Blood Stem Cell Transplantation / economics*
  • Peripheral Blood Stem Cell Transplantation / methods
  • Surveys and Questionnaires
  • Transplantation Conditioning
  • Transplantation, Autologous