Abstract
A 68-year-old man complaining of back pain was given the diagnosis of mucinous adenocarcinoma of the sigmoid colon with disseminated carcinomatosis of bone marrow and disseminated intravascular coagulation(DIC). We started chemotherapy using FOLFOX4. After we confirmed that DIC had improved following 2 courses of FOLFOX4, bevacizumab was added to FOLFOX4. Laboratory studies revealed a serum CEA level of 11, 432 ng/mL, which improved to 245 ng/mL after a total of 9 courses of chemotherapy. Chemotherapy is continuing as scheduled at 6 months from the onset of this disease.
Publication types
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Case Reports
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English Abstract
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Review
MeSH terms
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Adenocarcinoma, Mucinous / drug therapy*
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Adenocarcinoma, Mucinous / secondary
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Aged
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Antibodies, Monoclonal, Humanized / administration & dosage
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Antineoplastic Combined Chemotherapy Protocols / administration & dosage
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
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Bevacizumab
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Bone Marrow Neoplasms / drug therapy*
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Bone Marrow Neoplasms / secondary
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Fluorouracil / administration & dosage
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Humans
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Leucovorin / administration & dosage
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Male
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Organoplatinum Compounds / administration & dosage
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Sigmoid Neoplasms / drug therapy*
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Sigmoid Neoplasms / pathology
Substances
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Antibodies, Monoclonal, Humanized
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Organoplatinum Compounds
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Bevacizumab
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Leucovorin
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Fluorouracil