Low-fat and high-fat dairy products are differently related to blood lipids and cardiovascular risk score

Eur J Prev Cardiol. 2014 Dec;21(12):1557-67. doi: 10.1177/2047487313503283. Epub 2013 Sep 3.

Abstract

Background: Fat content of dairy foods is diverse, potentially leading to varying effects on cardiovascular risk. We studied relationships of low- and high-fat dairy products with lipids and level of cardiovascular risk (assessed by the SCORE equation), in a cross-sectional population survey conducted in three French areas.

Subjects and methods: A sample of 3078 participants aged 35-64 years underwent a standardized cardiovascular risk assessment. Subjects were asked to record the types and amounts of foods and beverages they consumed over a three-consecutive-day period. Dairy products were separated into two groups: the low-fat group comprised milk (including milk in desserts and beverages), yogurts and cottage cheese, whereas other cheeses formed the high-fat group.

Results: After adjustment (including physical activity and a diet quality score), the probability of an increased cardiovascular mortality score (≥1%) decreased from the lowest to the highest quartile (Q) of low-fat dairy intake: odds ratio (OR) ORQ1 = 1; ORQ2 = 0.89 (95% confidence interval: 0.73-1.10), ORQ3 = 0.78 (0.63-0.97) and ORQ4 = 0.68 (0.55-0.85) for the first, second, third and fourth quartile, respectively. Results were notably different for high-fat dairy intake: ORQ2 = 1.02 (0.82-1.25); ORQ3 = 0.90 (0.73-1.11); ORQ4 = 1.07 (0.86-1.32). Intake of low-fat dairy products was inversely associated with low-density lipoprotein cholesterol (LDL-C), but no significant independent relationship was found with high-density lipoprotein cholesterol (HDL-C) or triglycerides. None of the lipid parameters was significantly associated with the consumption of high-fat dairy products.

Conclusion: Participants with the highest intake of low-fat dairy products had the lowest mortality risk score and exhibited the best LDL-C profile. Such favourable associations were not observed with cheese consumption.

Keywords: Nutrition assessment; cardiovascular risk; dairy products; lipids.

Publication types

  • Comparative Study
  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Biomarkers / blood
  • Cardiovascular Diseases / blood
  • Cardiovascular Diseases / epidemiology*
  • Cardiovascular Diseases / mortality
  • Cardiovascular Diseases / prevention & control
  • Chi-Square Distribution
  • Cross-Sectional Studies
  • Dairy Products / adverse effects
  • Dairy Products / analysis*
  • Diet Records
  • Diet, Fat-Restricted* / adverse effects
  • Diet, High-Fat* / adverse effects
  • Dietary Fats / blood*
  • Feeding Behavior
  • Female
  • France / epidemiology
  • Health Surveys
  • Humans
  • Life Style
  • Linear Models
  • Logistic Models
  • Male
  • Middle Aged
  • Nutrition Assessment
  • Odds Ratio
  • Protective Factors
  • Risk Assessment
  • Risk Factors
  • Time Factors

Substances

  • Biomarkers
  • Dietary Fats