Rectal carcinoma in a young female patient with Peutz-Jeghers syndrome: a case report

Hsiang-Lin Tsai; Chih-Hung Lin; Ya-Lin Cheng; Ching-Wen Huang; Jaw-Yuan Wang

doi:10.1159/000351885

Rectal carcinoma in a young female patient with Peutz-Jeghers syndrome: a case report

Med Princ Pract. 2014;23(1):89-91. doi: 10.1159/000351885. Epub 2013 Sep 3.

Authors

Hsiang-Lin Tsai¹, Chih-Hung Lin, Ya-Lin Cheng, Ching-Wen Huang, Jaw-Yuan Wang

Affiliation

¹ Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, ROC.

Abstract

Objective: To report a case of rectal cancer in a patient with Peutz-Jeghers syndrome (PJS).

Clinical presentation and intervention: A 20-year-old woman with intermittent bloody stool of 4 months was admitted for examination. Gastroendoscopy revealed multiple polyps involving the stomach, small intestine, colon and a rectal adenocarcinoma. A diagnosis of PJS was made based on intestinal polyps with characteristic pathology and melanotic macules on the lips. After surgery and chemotherapy upon follow-up at 8 months, the patient did not have any signs of recurrence.

Conclusion: This case showed that rectal carcinoma should be considered for young patients with PJS.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Diagnosis, Differential
Female
Humans
Peutz-Jeghers Syndrome / diagnosis
Peutz-Jeghers Syndrome / epidemiology*
Peutz-Jeghers Syndrome / therapy
Rectal Neoplasms / epidemiology*
Rectal Neoplasms / therapy