Radiation-induced primary cerebral atypical teratoid/rhabdoid tumour in an adult

J Clin Neurosci. 2013 Oct;20(10):1466-8. doi: 10.1016/j.jocn.2013.03.041. Epub 2013 Sep 7.

Abstract

Atypical teratoid/rhabdoid tumours (ATRT) of the central nervous system are uncommon embryonal carcinomas that predominantly affect infants and young children, and less commonly adults. We report a 58 year old woman who presented with ATRT involving the right parietal lobe which was treated with surgery and adjuvant radiotherapy. Her history was significant for soft tissue sarcoma of the right ear treated with surgery and adjuvant radiotherapy at age 3, thus raising the possibility of radiation-induced aetiology.

Keywords: ATRT; Adult; Atypical; CNS; Radiotherapy.

Publication types

  • Case Reports

MeSH terms

  • Brain Neoplasms / etiology*
  • Brain Neoplasms / surgery
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Middle Aged
  • Parietal Lobe / pathology
  • Parietal Lobe / radiation effects
  • Rhabdoid Tumor / etiology*
  • Rhabdoid Tumor / surgery
  • Sarcoma / radiotherapy
  • Skin Neoplasms / radiotherapy
  • Tomography Scanners, X-Ray Computed