Surgical aortic valve replacement in very elderly patients aged 80 years and over: evaluation of early clinical outcomes

Heart Lung Circ. 2014 Mar;23(3):242-8. doi: 10.1016/j.hlc.2013.08.001. Epub 2013 Sep 7.

Abstract

Background: An increasing number of very elderly patients aged ≥80 years will require aortic valve replacement (AVR) for severe aortic stenosis (AS). Many are classified as high-risk surgical candidates. Transcatheter aortic valve implantation (TAVI) has been proposed as an alternative to surgical AVR (SAVR) for high-risk patients. We evaluated early clinical outcomes of very elderly patients undergoing SAVR to optimise TAVI candidate selection.

Methods: We conducted a retrospective case review of 132 consecutive patients aged ≥80 years undergoing isolated SAVR (49 patients) or combined SAVR/CABG (83 patients) during February 2002-January 2010 at a single tertiary referral hospital. Risk for cardiac surgery was calculated using the logistic EuroSCORE (ES(log)). Mortality and morbidity data were collected for the 30-day postoperative period.

Results: Thirty-day mortality rate was 8.3% for patients undergoing SAVR (6.1% for isolated SAVR and 9.6% for SAVR/CABG). Permanent stroke occurred in 3.8% and renal insufficiency in 7.6% of the cohort. Thirty-five percent of patients had left ventricular ejection fraction <50%, 67% had advanced symptoms (NYHA class III or IV), and 42% of patients were stratified as high-risk (ES(log)≥20%).

Conclusions: SAVR can be performed in very elderly patients with acceptable operative morbidity and mortality. The outcomes at our institution are comparable to contemporary SAVR and TAVI outcomes.

Keywords: Aortic stenosis; Aortic valve replacement; Elderly; Octogenarians; Transcatheter aortic valve implantation.

Publication types

  • Clinical Trial

MeSH terms

  • Aged, 80 and over
  • Aortic Valve Stenosis / mortality
  • Aortic Valve Stenosis / surgery*
  • Female
  • Follow-Up Studies
  • Health Services for the Aged*
  • Heart Valve Prosthesis Implantation / adverse effects
  • Heart Valve Prosthesis Implantation / methods*
  • Heart Valve Prosthesis*
  • Humans
  • Male
  • Renal Insufficiency / etiology
  • Renal Insufficiency / mortality
  • Retrospective Studies
  • Risk Factors
  • Stroke / etiology
  • Stroke / mortality
  • Time Factors