Azacitidine induces profound genome-wide hypomethylation in primary myelodysplastic bone marrow cultures but may also reduce histone acetylation

Leukemia. 2014 Feb;28(2):411-3. doi: 10.1038/leu.2013.265. Epub 2013 Sep 12.

¹ Department of Medicine, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden.
² Department of Bioscience and Nutrition, Karolinska Institutet, Stockholm, Sweden.
³ Center for Bioscience, Karolinska Institutet, Stockholm, Sweden.
⁴ 1] Department of Bioscience and Nutrition, Karolinska Institutet, Stockholm, Sweden [2] Center for Bioscience, Karolinska Institutet, Stockholm, Sweden [3] Molecular Medicine Research Program, Biomedicum, University of Helsinki and Folkhälsan Institute of Genetics, Helsinki, Finland.
⁵ 1] Department of Bioscience and Nutrition, Karolinska Institutet, Stockholm, Sweden [2] Molecular Medicine Research Program, Biomedicum, University of Helsinki and Folkhälsan Institute of Genetics, Helsinki, Finland.

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