Abstract
Clindamycin is increasingly used to treat canine pyoderma. Eight of 608 Staphylococcus pseudintermedius isolates were positive for inducible clindamycin resistance by double-disk diffusion testing and PCR detection of ermB. Staphylococcus pseudintermedius isolates that are erythromycin resistant but clindamycin susceptible by in vitro antimicrobial susceptibility testing should be tested for inducible clindamycin resistance.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Animals
-
Anti-Bacterial Agents / pharmacology*
-
Clindamycin / pharmacology*
-
Dog Diseases / epidemiology*
-
Dog Diseases / microbiology
-
Dogs
-
Drug Resistance, Bacterial*
-
Erythromycin / pharmacology
-
Gene Expression Regulation, Bacterial*
-
Genes, Bacterial
-
Incidence
-
Methyltransferases / genetics
-
Microbial Sensitivity Tests
-
Polymerase Chain Reaction
-
Staphylococcal Infections / epidemiology
-
Staphylococcal Infections / microbiology
-
Staphylococcal Infections / veterinary*
-
Staphylococcus / drug effects*
-
Staphylococcus / isolation & purification
Substances
-
Anti-Bacterial Agents
-
Clindamycin
-
Erythromycin
-
Methyltransferases