Pediatricians' perceptions of vaccine effectiveness and safety are significant predictors of vaccine administration in India

Int Health. 2013 Sep;5(3):205-10. doi: 10.1093/inthealth/iht018. Epub 2013 Jul 29.

Abstract

Background: New vaccine introduction is important to decrease morbidity and mortality in India. The goal of this study was to identify perceptions that are associated with administration of four selected vaccines for prevention of Japanese encephalitis (JE), typhoid fever, influenza and human papillomavirus (HPV) infection.

Methods: A random sample of 785 pediatricians from a national list of Indian Academy of Pediatrics members was selected for a survey to assess perceptions of vaccine effectiveness and safety, and vaccine administration practices. Logistic regression was used to assess factors associated with selective or routine use.

Results: Pediatricians reported administering typhoid (91.6%), influenza (60.1%), HPV (46.0%) and JE (41.9%) vaccines selectively or routinely. Pediatricians who perceived the vaccine to be safe were significantly more likely to report administration of JE (OR 2.6, 95% CI 1.3 to 5.3), influenza (OR 4.3, 95% CI 2.0 to 9.6) and HPV vaccine (OR 6.2, 95% CI 3.1 to 12.7). Pediatricians who perceived the vaccine to be effective were significantly more likely to report administration of JE (OR 3.3, 95% CI 1.6 to 6.5), influenza (OR 7.7, 95% CI 2.5 to 23.1) and HPV vaccine (OR 3.2, 95% CI 1.6 to 6.4) CONCLUSION: Understanding the role perceptions play provides an opportunity to design strategies to build support for vaccine use.

Keywords: Human papillomavirus vaccine; India; Influenza vaccine; Japanese encephalitis vaccine; Typhoid vaccine.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Attitude of Health Personnel*
  • Humans
  • India
  • Influenza Vaccines / administration & dosage
  • Influenza Vaccines / adverse effects
  • Japanese Encephalitis Vaccines / administration & dosage
  • Japanese Encephalitis Vaccines / adverse effects
  • Odds Ratio
  • Papillomavirus Vaccines / administration & dosage
  • Papillomavirus Vaccines / adverse effects
  • Patient Safety*
  • Pediatrics*
  • Physicians*
  • Treatment Outcome
  • Typhoid-Paratyphoid Vaccines / administration & dosage
  • Typhoid-Paratyphoid Vaccines / adverse effects
  • Vaccination* / adverse effects
  • Vaccines / administration & dosage*
  • Vaccines / adverse effects

Substances

  • Influenza Vaccines
  • Japanese Encephalitis Vaccines
  • Papillomavirus Vaccines
  • Typhoid-Paratyphoid Vaccines
  • Vaccines