Living-donor liver transplantation: donor selection criteria and postoperative outcomes. A single-center experience with a 10-year follow-up

Transplant Proc. 2013 Sep;45(7):2680-3. doi: 10.1016/j.transproceed.2013.07.037.

Abstract

Background: Donor safety must be considered to be a priority in live-donor liver transplantation (LDLT). The aim of this study was to evaluate these outcomes with special attention to surgical complications and their treatment.

Methods: From March 2001 to March 2012, 80 live donors underwent right hepatectomy (5-8 segments). The middle hepatic vein was always left in the donor. Our retrospective study analyzed surgical outcomes and complications according to the Clavien classification modified for live donors.

Results: With a median follow up of 63.2 ± 12.6 months, the mortality was 0%. Two donors experienced intraoperative complications, but all of them had complete recovery there after. Among the 22 complications in 17 donors (21.2%), 7 (8.7%) were major complications (Clavien grade 2b) but only 2 donors required surgical treatment.

Conclusions: LDLT is a safe and feasible modality to alleviate the cadaveric donor shortage. The efficacy of this procedure is similar to that with deceased donors.

MeSH terms

  • Adult
  • Female
  • Follow-Up Studies
  • Humans
  • Liver Transplantation*
  • Living Donors*
  • Male
  • Middle Aged
  • Treatment Outcome
  • Young Adult