An ultrasensitive aptameric sensor for proteins based on hyperbranched rolling circle amplification

Chem Commun (Camb). 2013 Oct 3;49(86):10115-7. doi: 10.1039/c3cc45521a.

Abstract

A novel fluorescent aptameric sensor for thrombin has been developed by combination of the high amplification efficiency of HRCA and the specific function of aptameric recognition.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aptamers, Nucleotide / chemistry*
  • Biosensing Techniques / methods*
  • Fluorescent Dyes / chemistry*
  • Humans
  • Proteins / analysis*
  • Thrombin / analysis

Substances

  • Aptamers, Nucleotide
  • Fluorescent Dyes
  • Proteins
  • Thrombin