Abstract
The prevalence of hepatitis C virus (HCV) infection in sub-Saharan Africa remains unclear. We tested 1000 individuals from Rakai, Uganda, with the Ortho version 3.0 HCV enzyme-linked immunosorbent assay. All serologically positive samples were tested for HCV RNA. Seventy-six of the 1000 (7.6%) participants were HCV antibody positive; none were confirmed by detection of HCV RNA.
Keywords:
Africa; ELISA; hepatitis C virus.
Publication types
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Research Support, N.I.H., Intramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Analysis of Variance
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Enzyme-Linked Immunosorbent Assay / statistics & numerical data*
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False Positive Reactions
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Female
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HIV Infections / blood
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HIV Infections / etiology
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HIV Infections / virology
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Hepacivirus / immunology
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Hepacivirus / isolation & purification
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Hepatitis C / diagnosis*
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Hepatitis C / epidemiology
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Hepatitis C / immunology
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Hepatitis C / virology
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Hepatitis C Antibodies / blood
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Humans
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Male
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Middle Aged
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Prevalence
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RNA, Viral / blood
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Seroepidemiologic Studies
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Uganda / epidemiology
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Young Adult
Substances
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Hepatitis C Antibodies
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RNA, Viral