Dynamics of the Romanian waiting list for liver transplantation after changing organ allocation policy

J Gastrointestin Liver Dis. 2013 Sep;22(3):299-303.

Abstract

Aim: The aim of the present study was to characterize the dynamics of the Romanian waiting list (WL) for liver transplantation (LT) over two periods: 2004-2007 vs. 2008-2011.

Methods: 1,085 patients listed for LT during the time period 2004-2011 were included in our analysis.

Results: Death on the WL was significantly higher before 2008 (37% vs. 26.4%, p=0.0001) and risk of dying while on WL was 60% higher. Waiting time on the WL was 75% longer and time until LT was 102% longer before 2008 compared to the second time period (p=0.0001). After 2008, 62.3% of patients were listed for LT with Child Pugh class C compared to 22.1% before 2008 (p<0.0001).

Conclusion: A significant reduction of mortality has been registered on the Romanian WL for LT after 2008, despite the increased severity of liver disease in patients listed for LT.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Chi-Square Distribution
  • Female
  • Humans
  • Kaplan-Meier Estimate
  • Liver Diseases / diagnosis
  • Liver Diseases / mortality
  • Liver Diseases / surgery*
  • Liver Transplantation*
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Policy Making*
  • Proportional Hazards Models
  • Retrospective Studies
  • Risk Factors
  • Romania
  • Severity of Illness Index
  • Time Factors
  • Tissue and Organ Procurement / organization & administration*
  • Waiting Lists* / mortality