Abstract
A newly demonstrated defect in RNA polymerase II termination caused by 7SK snRNA knockdown may have revealed a novel mechanism uncoupling RNA processing from transcription.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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3' Untranslated Regions
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Animals
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Chromatin / chemistry
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Chromatin / metabolism
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Embryonic Stem Cells / cytology
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Embryonic Stem Cells / metabolism*
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Gene Expression Regulation, Developmental*
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Genetic Loci
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Genome*
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Mice
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Polyadenylation
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Promoter Regions, Genetic
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RNA Polymerase II / genetics*
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RNA Polymerase II / metabolism
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RNA, Small Interfering / genetics
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RNA, Small Interfering / metabolism
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RNA, Small Nuclear / antagonists & inhibitors
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RNA, Small Nuclear / genetics*
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RNA, Small Nuclear / metabolism
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Transcription Termination, Genetic*
Substances
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3' Untranslated Regions
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Chromatin
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RNA, Small Interfering
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RNA, Small Nuclear
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RNA Polymerase II