Extended-spectrum beta-lactamase-producing Enterobacteriaceae carriage upon hospital admission: prevalence and risk factors

J Hosp Infect. 2013 Nov;85(3):230-2. doi: 10.1016/j.jhin.2013.07.014. Epub 2013 Sep 8.

Abstract

The aim of this study was to assess the value of surveillance cultures in identifying extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL) carriers upon admission to hospital, and to identify risk factors for carriage. This prospective cross-sectional study included all hospital admissions over one week. Of 525 patients screened, 56 were positive for ESBLs. Half were only identified through screening. Four independent risk factors were identified: nursing home residency, hospitalization in the previous year, prior antibiotic treatment and prior ESBL carriage. Over 50% of the screened patients had at least one risk factor. By screening this targeted population, 87.5% of positive patients would have been identified.

Keywords: ESBL; Risk factors; Surveillance.

MeSH terms

  • Aged
  • Carrier State / epidemiology*
  • Carrier State / microbiology
  • Cross-Sectional Studies
  • Diagnostic Tests, Routine
  • Enterobacteriaceae / enzymology*
  • Enterobacteriaceae / isolation & purification
  • Enterobacteriaceae Infections / epidemiology*
  • Enterobacteriaceae Infections / microbiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • Prospective Studies
  • Risk Factors
  • beta-Lactamases / metabolism*

Substances

  • beta-Lactamases