Outcomes of transoral laser microsurgery for recurrent head and neck cancer

J Laryngol Otol. 2013 Oct;127(10):982-6. doi: 10.1017/S0022215113001953. Epub 2013 Oct 7.

Abstract

Objective: To report our outcomes with salvage CO2 laser surgery following recurrence of laryngeal and oropharyngeal cancer after radiotherapy.

Method: This study entailed a prospective review of patients treated with transoral laser microsurgery for recurrent laryngeal and oropharyngeal cancer between 2002 and 2010 at the Queen Elizabeth II Health Science Centre in Canada.

Results: Sixteen patients were identified, with a mean follow up of 30.6 months. Five patients died of recurrence. Complications were common in patients with oropharyngeal cancer. The overall survival and disease-free survival rates at an average of 29.8 months follow up were 50 per cent and 68.8 per cent respectively.

Conclusion: Salvage surgery using transoral laser microsurgery should be considered in the management of patients with recurrent laryngeal and oropharyngeal cancer. This technique offers acceptable salvage rates with less comorbidity than other treatments.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Canada / epidemiology
  • Carcinoma, Squamous Cell / mortality
  • Carcinoma, Squamous Cell / radiotherapy
  • Carcinoma, Squamous Cell / surgery*
  • Disease-Free Survival
  • Female
  • Glottis / surgery
  • Head and Neck Neoplasms / mortality
  • Head and Neck Neoplasms / radiotherapy
  • Head and Neck Neoplasms / surgery*
  • Humans
  • Laryngeal Neoplasms / mortality
  • Laryngeal Neoplasms / radiotherapy
  • Laryngeal Neoplasms / surgery*
  • Laser Therapy / methods*
  • Lasers, Gas
  • Male
  • Microsurgery / methods
  • Middle Aged
  • Neoplasm Recurrence, Local / surgery*
  • Oropharyngeal Neoplasms / mortality
  • Oropharyngeal Neoplasms / radiotherapy
  • Oropharyngeal Neoplasms / surgery*
  • Prospective Studies
  • Salvage Therapy*
  • Squamous Cell Carcinoma of Head and Neck