The feasibility study on 3-dimensional fluorescent x-ray computed tomography using the pinhole effect for biomedical applications

Annu Int Conf IEEE Eng Med Biol Soc. 2013:2013:2348-51. doi: 10.1109/EMBC.2013.6610009.

Abstract

We propose a 3-dimensional fluorescent x-ray computed tomography (CT) pinhole collimator, aimed at providing molecular imaging with quantifiable measures and sub-millimeter spatial resolution. In this study, we demonstrate the feasibility of this concept and investigate imaging properties such as spatial resolution, contrast resolution and quantifiable measures, by imaging physical phantoms using a preliminary imaging system developed with monochromatic synchrotron x rays constructed at the BLNE-7A experimental line at KEK, Japan.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Feasibility Studies
  • Humans
  • Imaging, Three-Dimensional
  • Phantoms, Imaging
  • Radiographic Image Interpretation, Computer-Assisted
  • Tomography, X-Ray Computed / methods*