Single non-inactivating K+ channels in the myotubes of the chick embryo in tissue culture

Gen Physiol Biophys. 1985 Jun;4(3):241-8.

Abstract

Single-channel K+ currents were studied in the myotubes from the chick embryo grown in tissue culture for 4--9 days by employing the patch clamp technique. The "cell attached" configuration was used and the pipette was filled with a solution containing 3 mmol.l-1 K+. The channels exhibited a high conductance of approximately 90 pS and the probability of finding them open increased by an e-fold factor for 13 mV depolarization for low levels of activity. The channels did not inactivate during long-lasting depolarization. These channels have been suggested to contribute to delayed rectification.

MeSH terms

  • Animals
  • Chick Embryo
  • Ion Channels / analysis*
  • Membrane Potentials
  • Muscles / analysis*
  • Muscles / embryology
  • Time Factors

Substances

  • Ion Channels