Global profiling of carbonyl metabolites with a photo-cleavable isobaric labeling affinity tag

Chem Commun (Camb). 2013 Dec 7;49(94):11080-2. doi: 10.1039/c3cc45956j.

Abstract

A carbonyl-reactive photo-cleavable isobaric labeling affinity tag can provide a selective, high-throughput, and reproducible approach for the quantitative analysis of aldehyde and ketone metabolites in complex biological samples.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehydes / chemistry*
  • Aldehydes / metabolism*
  • Indicators and Reagents / chemistry
  • Ketones / chemistry*
  • Ketones / metabolism*
  • Photochemical Processes*
  • Staining and Labeling / methods*
  • Substrate Specificity

Substances

  • Aldehydes
  • Indicators and Reagents
  • Ketones