Integration of stable isotope and trace contaminant concentration for enhanced forensic acetone discrimination

Talanta. 2013 Nov 15:116:866-9. doi: 10.1016/j.talanta.2013.07.015. Epub 2013 Jul 18.

Abstract

We analyzed 21 neat acetone samples from 15 different suppliers to demonstrate the utility of a coupled stable isotope and trace contaminant strategy for distinguishing forensically-relevant samples. By combining these two pieces of orthogonal data we could discriminate all of the acetones that were produced by the 15 different suppliers. Using stable isotope ratios alone, we were able to distinguish 8 acetone samples, while the remaining 13 fell into four clusters with highly similar signatures. Adding trace chemical contaminant information enhanced discrimination to 13 individual acetones with three residual clusters. The acetones within each cluster shared a common manufacturer and might, therefore, not be expected to be resolved. The data presented here demonstrates the power of combining orthogonal data sets to enhance sample fingerprinting and highlights the role disparate data could play in future forensic investigations.

Keywords: Acetone; Forensic fingerprinting; Stable isotope; Trace contaminant analysis.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Acetone / classification
  • Acetone / isolation & purification*
  • Carbon Isotopes
  • Chemical Terrorism / prevention & control
  • Deuterium
  • Discriminant Analysis
  • Forensic Sciences / instrumentation
  • Forensic Sciences / methods*
  • Hexanones / isolation & purification
  • Humans
  • Ketones / isolation & purification
  • Mass Spectrometry / statistics & numerical data*
  • Pentanols / isolation & purification
  • Pentanones / isolation & purification

Substances

  • Carbon Isotopes
  • Hexanones
  • Ketones
  • Pentanols
  • Pentanones
  • Acetone
  • mesityl oxide
  • phorone
  • Deuterium
  • diacetone alcohol