Clear cell adenocarcinoma arising from clear cell adenofibroma of the ovary: value of DWI and DCE-MRI

Magn Reson Med Sci. 2013 Dec 25;12(4):305-8. doi: 10.2463/mrms.2013-0001. Epub 2013 Oct 29.

Abstract

Clear cell adenofibroma (CCAF) is a rare surface epithelial-stromal tumor of the ovary and recently considered another precursor of clear cell adenocarcinoma (CCA) other than endometrioma. We report magnetic resonance (MR) findings of a borderline CCAF that contained a small CCA focus. The tumor manifested a characteristic "black sponge" appearance. The CCA focus showed high signal intensity on diffusion-weighted imaging (DWI) and early enhancement on dynamic contrast-enhanced (DCE) MR imaging (DCE-MRI), and the CCAF components showed low signal intensity on DWI and gradually increasing contrast enhancement on DCE-MRI.

Publication types

  • Case Reports
  • Comparative Study

MeSH terms

  • Adenocarcinoma, Clear Cell / pathology*
  • Cell Transformation, Neoplastic / pathology*
  • Cystadenofibroma / pathology*
  • Diagnosis, Differential
  • Diffusion Magnetic Resonance Imaging / methods*
  • Female
  • Humans
  • Middle Aged
  • Ovarian Neoplasms / pathology*