Myeloma after local external beam radiotherapy jet: Is it a new entity?

Cancer Radiother. 2013 Nov;17(7):668-70. doi: 10.1016/j.canrad.2013.09.003. Epub 2013 Oct 28.

Abstract

Multiple myeloma, also known as Kahler's disease, is a cancer of plasma cells that abnormally accumulate in bone marrow. Radiation therapy may be indicated in multiple myeloma to relieve pain, alleviate spinal cord compression or reduce tumor mass. We report the case of a patient presenting a multiple myeloma, treated with radiation therapy for a spinal cord compression, who developed, eleven months later, an in-field subcutaneous relapse. We called this phenomenon myeloma appearance after local external beam radiotherapy jet (MAALEJ). A review of literature was performed trying to explain this uncommon relapse feature.

Keywords: Champ; Cutaneous; Cutané; Field; Multiple myeloma; Myélome multiple; Radiation therapy; Radiothérapie; Relapse; Récidive.

Publication types

  • Case Reports

MeSH terms

  • Female
  • Humans
  • Middle Aged
  • Multiple Myeloma / complications
  • Multiple Myeloma / radiotherapy*
  • Neoplasm Recurrence, Local / pathology
  • Neoplasm Recurrence, Local / radiotherapy
  • Skin Neoplasms / pathology*
  • Skin Neoplasms / radiotherapy
  • Spinal Cord Compression / etiology
  • Spinal Cord Compression / therapy