Optimization of the parameters for diffusion tensor magnetic resonance imaging data acquisition for breast fiber tractography at 1.5 T

Introduction: Diffusion tensor MRI has emerged as a promising tool for the analysis of the microscopic properties of tissues. Optimizing image acquisition parameters is essential for producing high-quality DTI. This study aimed to optimize the parameters for DTI data acquisition for breast fiber tractography at 1.5 T.

Patients and methods: A total of 21 healthy volunteers received breast DTI scanning using an ASSET-based EPI technique operated under different parameters including b value, the number of diffusion gradient directions, and spatial resolution. The images were analyzed for signal-to-noise, signal intensity ratio, mean number and length of reconstructive fiber tracts, and fractional anisotropy value.

Results: The optimal acquisition parameters at 1.5 T for breast DT-MRI fiber tractography were determined as follows: axial 31 direction, b = 600 seconds per mm(2), matrix 128 × 128 with slice thickness of 3 mm.

Conclusion: The optimization of data acquisition parameters could improve the quality of breast DT-MRI images and assist fiber tractography at 1.5 T.