No abstract available
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Cell Proliferation / drug effects*
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Colonic Neoplasms / drug therapy*
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Colonic Neoplasms / genetics
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Colonic Neoplasms / pathology
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Humans
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Imidazoles / therapeutic use
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MAP Kinase Kinase 1 / antagonists & inhibitors
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MAP Kinase Kinase 1 / metabolism
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MAP Kinase Kinase 2 / antagonists & inhibitors
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MAP Kinase Kinase 2 / metabolism
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Male
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Middle Aged
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Mutation*
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Oximes / therapeutic use
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Protein Kinase Inhibitors / therapeutic use*
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Proto-Oncogene Proteins / genetics*
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Proto-Oncogene Proteins B-raf / antagonists & inhibitors
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Proto-Oncogene Proteins B-raf / metabolism
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Proto-Oncogene Proteins p21(ras)
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Pyridones / therapeutic use
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Pyrimidinones / therapeutic use
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Treatment Outcome
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ras Proteins / genetics*
Substances
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Imidazoles
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KRAS protein, human
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Oximes
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Protein Kinase Inhibitors
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Proto-Oncogene Proteins
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Pyridones
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Pyrimidinones
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trametinib
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Proto-Oncogene Proteins B-raf
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MAP Kinase Kinase 1
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MAP Kinase Kinase 2
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Proto-Oncogene Proteins p21(ras)
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ras Proteins
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dabrafenib