Effect of vitamin D status on pharmacological treatment efficiency: Impact on cost-effective management in medicine

Dermatoendocrinol. 2013 Apr 1;5(2):299-304. doi: 10.4161/derm.25279.

Abstract

At least 80% of the whole Polish population, including prepubertal children and adolescents, adults and seniors, are vitamin D deficient, defined as 25(OH)D < 50 nmol/L. 83% of Polish newborns start their lives at the state of vitamin D deficiency because 78% of their mothers are also deficient. It was observed that treating patient vitamin D deficiency to vitamin D status serum 25(OH)D) 75-100 nmol/L increased effectiveness of therapies in infectious diseases (chronic hepatitis C, tuberculosis), osteoporosis, multiple sclerosis, epilepsy, Chronic Kidney Diseases and atopic dermatitis. . For these reasons doctors should take special attention to vitamin D status in patients suffering for these diseases properly implementing recent vitamin D recommendation.

Keywords: 25-hydroxyvitamin D; atopic dermatitis; chronic hepatitis C; epilepsy; multiple sclerosis; osteoporosis; tuberculosis; vitamin D deficiency.