Cervical spondylitis and spinal abscess due to Actinomyces meyeri

Braz J Infect Dis. 2014 Jan-Feb;18(1):106-9. doi: 10.1016/j.bjid.2013.05.016. Epub 2013 Nov 7.

Abstract

Human actinomycosis with involvement of the spine is a rare condition although it has been first described a long time ago. It is probably underrecognized since its clinical presentation is often misleading and accurate bacteriological diagnosis is challenging. We herein report a rare case of cervical actinomycosis with paravertebral abscess and spondylitis imputed to an infection by Actinomyces meyeri in a 52-year-old immunocompetent Caucasian man. A. meyeri should be considered as a potential cause for subacute or chronic spondylitis, even in immunocompetent subjects. Modern diagnostic tools such as Matrix-Assisted Laser Desorption-Ionization Time of Flight mass spectrometry and 16S rRNA sequencing are efficient for accurate microbiological identification.

Keywords: 16S rRNA; Actinomyces; MALDI–TOF mass spectrometry; Spondylitis.

Publication types

  • Case Reports

MeSH terms

  • Abscess / diagnosis
  • Abscess / microbiology*
  • Actinomyces / genetics
  • Actinomyces / isolation & purification*
  • Actinomycosis / diagnosis*
  • Cervical Vertebrae / microbiology*
  • DNA, Bacterial / genetics
  • Humans
  • Immunocompetence
  • Male
  • Middle Aged
  • Polymerase Chain Reaction
  • RNA, Ribosomal, 16S / genetics
  • Spinal Diseases / diagnosis
  • Spinal Diseases / microbiology*
  • Spondylitis / diagnosis
  • Spondylitis / microbiology*

Substances

  • DNA, Bacterial
  • RNA, Ribosomal, 16S