On the way towards a 'CLL prognostic index': focus on TP53, BIRC3, SF3B1, NOTCH1 and MYD88 in a population-based cohort

Leukemia. 2014 Mar;28(3):710-3. doi: 10.1038/leu.2013.333. Epub 2013 Nov 12.

Authors

D Cortese¹, L-A Sutton¹, N Cahill¹, K E Smedby², C Geisler³, R Gunnarsson¹, G Juliusson⁴, L Mansouri¹, R Rosenquist¹

Affiliations

¹ Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
² Department of Medicine, Clinical Epidemiology Unit, Karolinska Institutet, Stockholm, Sweden.
³ Department of Hematology, Leukemia Laboratory, Rigshospitalet, Copenhagen, Denmark.
⁴ Department of Laboratory Medicine, Stem Cell Center, Hematology and Transplantation, Lund University, Lund, Sweden.

PMID: 24217197
DOI: 10.1038/leu.2013.333

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Baculoviral IAP Repeat-Containing 3 Protein
Cohort Studies
Humans
Inhibitor of Apoptosis Proteins / genetics
Leukemia, Lymphocytic, Chronic, B-Cell / genetics*
Myeloid Differentiation Factor 88 / genetics
Phosphoproteins / genetics
Prognosis
RNA Splicing Factors
Receptor, Notch1 / genetics
Ribonucleoprotein, U2 Small Nuclear / genetics
Tumor Suppressor Protein p53 / genetics
Ubiquitin-Protein Ligases

Substances

Inhibitor of Apoptosis Proteins
MYD88 protein, human
Myeloid Differentiation Factor 88
NOTCH1 protein, human
Phosphoproteins
RNA Splicing Factors
Receptor, Notch1
Ribonucleoprotein, U2 Small Nuclear
SF3B1 protein, human
Tumor Suppressor Protein p53
BIRC3 protein, human
Baculoviral IAP Repeat-Containing 3 Protein
Ubiquitin-Protein Ligases