ClockstaR: choosing the number of relaxed-clock models in molecular phylogenetic analysis

Bioinformatics. 2014 Apr 1;30(7):1017-9. doi: 10.1093/bioinformatics/btt665. Epub 2013 Nov 14.

Abstract

Summary: Relaxed molecular clocks allow the phylogenetic estimation of evolutionary timescales even when substitution rates vary among branches. In analyses of large multigene datasets, it is often appropriate to use multiple relaxed-clock models to accommodate differing patterns of rate variation among genes. We present ClockstaR, a method for selecting the number of relaxed clocks for multigene datasets.

Availability: ClockstaR is freely available for download at http://sydney.edu.au/science/biology/meep/software/.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Databases, Genetic
  • Genomics / methods*
  • High-Throughput Nucleotide Sequencing / methods*
  • Models, Genetic
  • Phylogeny*
  • Software Design