Management of end-stage liver disease

Med Clin North Am. 2014 Jan;98(1):119-52. doi: 10.1016/j.mcna.2013.09.006. Epub 2013 Oct 30.

Abstract

Patients with cirrhosis who experience hepatic decompensation, such as the development of ascites, SBP, variceal hemorrhage, or hepatic encephalopathy, or who develop HCC, are at a higher risk of mortality. Management should be focused on the prevention of recurrence of complications, and these patients should be referred for consideration of liver transplantation.

Keywords: Ascites; Cirrhosis; Decompensation; Hepatic encephalopathy; Peritonitis; Varices.

Publication types

  • Review

MeSH terms

  • Ascites / etiology
  • Ascites / therapy
  • Carcinoma, Hepatocellular* / complications
  • Carcinoma, Hepatocellular* / diagnosis
  • Disease Management
  • Disease Progression
  • End Stage Liver Disease* / diagnosis
  • End Stage Liver Disease* / etiology
  • End Stage Liver Disease* / physiopathology
  • End Stage Liver Disease* / prevention & control
  • Esophageal and Gastric Varices / etiology
  • Esophageal and Gastric Varices / therapy
  • Gastrointestinal Hemorrhage / etiology
  • Gastrointestinal Hemorrhage / therapy
  • Hepatic Encephalopathy / etiology
  • Hepatic Encephalopathy / therapy
  • Humans
  • Liver / diagnostic imaging
  • Liver Cirrhosis* / complications
  • Liver Cirrhosis* / diagnosis
  • Liver Cirrhosis* / therapy
  • Liver Neoplasms* / complications
  • Liver Neoplasms* / diagnosis
  • Liver Transplantation / methods*
  • Mass Screening / methods
  • Neoplasm Staging
  • Ultrasonography