[Treatment of type 2 diabetes mellitus in patients with chronic kidney disease. Grupo de Trabajo para el Documento de Consenso sobre el tratamiento de la diabetes tipo 2 en el paciente con enfermedad renal crónica]

Med Clin (Barc). 2014 Jan 21;142(2):85.e1-10. doi: 10.1016/j.medcli.2013.10.011. Epub 2013 Nov 21.
[Article in Spanish]

Abstract

Chronic kidney disease (CKD) and type 2 diabetes mellitus (T2DM) are highly prevalent chronic diseases, which represent an important public health problem and require a multidisciplinary management. T2DM is the main cause of CKD and it also causes a significant comorbidity with regard to non-diabetic nephropathy. Patients with diabetes and kidney disease represent a special risk group as they have higher morbi-mortality as well as higher risk of hypoglycemia than diabetic individuals with a normal kidney function. Treatment of T2DM in patients with CKD is controversial because of the scarcity of available evidence. The current consensus report aims to ease the appropriate selection and dosage of antidiabetic treatments as well as the establishment of safety objectives of glycemic control in patients with CKD.

Keywords: Ancianos; Cardiovascular risk factors; Chronic kidney disease; Diabetes mellitus tipo 2; Elderly; Enfermedad renal crónica; Factores de riesgo cardiovascular; Type 2 diabetes mellitus.

Publication types

  • Consensus Development Conference
  • Practice Guideline

MeSH terms

  • Albuminuria / etiology
  • Blood Glucose / analysis
  • Diabetes Mellitus, Type 2 / blood
  • Diabetes Mellitus, Type 2 / complications
  • Diabetes Mellitus, Type 2 / drug therapy*
  • Diabetic Nephropathies / etiology
  • Dyslipidemias / prevention & control
  • Glycated Hemoglobin / analysis
  • Humans
  • Hypertension / epidemiology
  • Hypoglycemia / chemically induced
  • Hypoglycemia / etiology
  • Hypoglycemia / prevention & control
  • Hypoglycemic Agents / adverse effects
  • Hypoglycemic Agents / pharmacokinetics
  • Hypoglycemic Agents / therapeutic use*
  • Platelet Aggregation Inhibitors / adverse effects
  • Platelet Aggregation Inhibitors / therapeutic use
  • Prognosis
  • Renal Insufficiency, Chronic / complications*
  • Renal Insufficiency, Chronic / metabolism
  • Vascular Diseases / epidemiology

Substances

  • Blood Glucose
  • Glycated Hemoglobin A
  • Hypoglycemic Agents
  • Platelet Aggregation Inhibitors