Deregulated type I IFN response in TREX1-associated familial chilblain lupus

J Invest Dermatol. 2014 May;134(5):1456-1459. doi: 10.1038/jid.2013.496. Epub 2013 Nov 22.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Autoimmunity / genetics*
  • Autoimmunity / immunology
  • Chilblains / genetics*
  • Chilblains / immunology
  • Chilblains / metabolism
  • Child
  • Exodeoxyribonucleases / genetics*
  • Exodeoxyribonucleases / immunology
  • Exodeoxyribonucleases / metabolism
  • Heterozygote
  • Humans
  • Interferon Type I / immunology
  • Interferon Type I / metabolism*
  • Lupus Erythematosus, Cutaneous / genetics*
  • Lupus Erythematosus, Cutaneous / immunology
  • Lupus Erythematosus, Cutaneous / metabolism
  • Mice
  • Mice, Knockout
  • Phosphoproteins / genetics*
  • Phosphoproteins / immunology
  • Phosphoproteins / metabolism

Substances

  • Interferon Type I
  • Phosphoproteins
  • Exodeoxyribonucleases
  • three prime repair exonuclease 1

Supplementary concepts

  • Chilblain lupus 1