[Treatment of 2 newborn infants with autoimmune thrombocytopenia by high-dose intravenous gamma globulins]

Arch Fr Pediatr. 1986 Mar;43(3):191-3.
[Article in French]

Abstract

We report 2 cases of neonatal auto-immune thrombocytopenia treated with high-dose intravenous gamma-globulins. Efficacy of treatment was immediate, inducing an increase in platelet levels which was transitory during the first 2 weeks but stabilized in the third week. Tolerance was excellent. Injections of 400 mg/kg/day repeated for 4 to 5 days should be preferred to a single dose of 1 to 2 g/kg.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Autoantibodies / analysis
  • Autoimmune Diseases / congenital
  • Autoimmune Diseases / therapy*
  • Blood Platelets / immunology
  • Female
  • Humans
  • Infant, Newborn
  • Injections, Intravenous
  • Male
  • Maternal-Fetal Exchange
  • Platelet Count
  • Pregnancy
  • Thrombocytopenia / congenital
  • Thrombocytopenia / therapy*
  • gamma-Globulins / administration & dosage*

Substances

  • Autoantibodies
  • gamma-Globulins