Abstract
We report 2 cases of neonatal auto-immune thrombocytopenia treated with high-dose intravenous gamma-globulins. Efficacy of treatment was immediate, inducing an increase in platelet levels which was transitory during the first 2 weeks but stabilized in the third week. Tolerance was excellent. Injections of 400 mg/kg/day repeated for 4 to 5 days should be preferred to a single dose of 1 to 2 g/kg.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Adult
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Autoantibodies / analysis
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Autoimmune Diseases / congenital
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Autoimmune Diseases / therapy*
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Blood Platelets / immunology
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Female
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Humans
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Infant, Newborn
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Injections, Intravenous
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Male
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Maternal-Fetal Exchange
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Platelet Count
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Pregnancy
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Thrombocytopenia / congenital
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Thrombocytopenia / therapy*
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gamma-Globulins / administration & dosage*
Substances
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Autoantibodies
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gamma-Globulins