Single-center experience of a quadripolar pacing lead for cardiac resynchronization therapy

J Interv Card Electrophysiol. 2014 Mar;39(2):161-5. doi: 10.1007/s10840-013-9849-8. Epub 2013 Nov 29.

Abstract

Aim: Recent studies have shown that a quadripolar left ventricular (LV) lead can result in low rates of dislocation and phrenic nerve stimulation (PNS) acutely and on medium-term follow-up in cardiac resynchronization therapy (CRT). We evaluated the outcomes of CRT patients in whom a quadripolar LV lead was implanted in our institution.

Methods: We studied 45 consecutive heart failure patients (75 % men; age, 70.3 ± 9.0 years) following successful implantation of a quadripolar LV lead. Demographic and clinical data were collected preoperatively, and patients were followed up for 18.9 months.

Results: The implantation success rate was 100 %. Mean overall duration was 100.1 ± 34.6 min, and X-ray exposure time was 13.20 ± 13.5 min. The most distal effective pacing site was used as the final pacing configuration in all patients. Acute dislodgment requiring reoperation occurred before discharge in three cases (6.6 %). Six patients (13 %) suffered PNS during follow-up; we solved this problem by changing the stimulation vector. Three months after implantation, a mean of six out of ten effective sites (threshold <2.5 V at 1.5 ms, no PNS) per patient was recorded.

Conclusions: Over the relatively long term, the quadripolar LV lead was associated with excellent pacing thresholds and low rates of dislocation and PNS.

Publication types

  • Clinical Trial

MeSH terms

  • Aged
  • Cardiac Resynchronization Therapy / adverse effects*
  • Cardiac Resynchronization Therapy / methods*
  • Cardiac Resynchronization Therapy Devices / adverse effects*
  • Electrodes, Implanted / adverse effects*
  • Equipment Design
  • Equipment Failure Analysis
  • Female
  • Foreign-Body Migration / etiology*
  • Foreign-Body Migration / prevention & control
  • Heart Failure / complications
  • Heart Failure / prevention & control*
  • Humans
  • Male
  • Treatment Outcome