We report the first successful use, to our knowledge, of fumagillin alone in a pediatric patient to cure intestinal microsporidiosis in a liver-kidney transplanted child. Detection of Enterocytozoon bieneusi in stool became negative from the first post-therapeutic control, while digestive symptoms disappeared in 4 days. During a 9-month follow-up, polymerase chain reaction and direct examinations remained negative for microsporidia in her feces. No major undesirable effects were noted during the anti-microsporidial therapy.
Keywords: Enterocytozoon bieneusi; PCR; fumagillin; intestinal microsporidiosis; liver-kidney transplant; pediatrics.
© 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.