Abstract
Electrostatic interaction-mediated enzymatic-hydrolysis of poly(lactide)-containing nanoscale assemblies is described. At physiological pH, degradable core-shell morphologies with charged shells can readily attract or repel enzymes carrying opposite or similar charges, respectively.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Enzymes / chemistry
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Enzymes / metabolism*
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Hydrogen-Ion Concentration
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Hydrolysis
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Micelles
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Nanostructures / chemistry
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Polyesters / chemistry
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Polyesters / metabolism*
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Static Electricity
Substances
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Enzymes
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Micelles
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Polyesters
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poly(lactide)