Renal artery thrombosis is a rare, but serious and often misdiagnosed, condition, with poor prognosis and renal functional impairment. As for the rarity of the occurrence, data about real incidence of renal stent thrombosis are lacking, ranging from 0 to 1 % depending on the study evaluated. We report the case of a 43-year-old man with nephrovascular hypertension, previously treated with renal stent implantation, with a late stent thrombosis. The diagnostic and subsequent therapeutic management was analyzed and discussed.