Nuclear division: giving daughters their fair share

Curr Biol. 2013 Dec 2;23(23):R1045-7. doi: 10.1016/j.cub.2013.10.041.

Abstract

How do nuclear components, apart from chromosomes, partition equally to daughter nuclei during mitosis? In Schizosaccharomyces japonicus, the conserved LEM-domain nuclear envelope protein Man1 ensures the formation of identical daughter nuclei by coupling nuclear pore complexes to the segregating chromosomes.

MeSH terms

  • Cell Nucleus Division / genetics*
  • Cell Nucleus Structures / genetics*
  • Chromosome Segregation / genetics*
  • Chromosomes / genetics
  • Mitosis
  • Nuclear Pore / genetics
  • Nuclear Pore Complex Proteins / genetics*
  • Schizosaccharomyces / genetics*
  • Schizosaccharomyces pombe Proteins / genetics

Substances

  • Nuclear Pore Complex Proteins
  • Schizosaccharomyces pombe Proteins