[Warfarin-related nephropathy: a case report]

Rev Med Interne. 2015 Jan;36(1):51-4. doi: 10.1016/j.revmed.2013.09.006. Epub 2013 Dec 3.
[Article in French]

Abstract

Introduction: Warfarin-related nephropathy (WRN) is a newly recognized entity, which is characterized by the occlusion of renal tubules by red blood cells following glomerular hemorrhage in a patient overexposed to warfarin (international normalized ratio>3).

Case report: We report a 70-year-old man with no previous renal condition who developed WRN when his INR was>12. He did not fully recover his previous renal function.

Conclusion: The diagnosis of WRN should be considered whenever INR exceeds 3 in patients exposed to warfarin, particularly in the presence of hematuria. Vitamin K is the only therapeutic option.

Keywords: Acute kidney injury; Anti-vitamine K; Coumadine; Insuffisance rénale aiguë; Vitamin K deficiency; Warfarin.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Acute Kidney Injury / chemically induced*
  • Acute Kidney Injury / therapy
  • Aged
  • Anticoagulants / administration & dosage
  • Anticoagulants / adverse effects*
  • Hematuria / chemically induced
  • Hematuria / therapy
  • Humans
  • Male
  • Medication Errors
  • Renal Dialysis
  • Warfarin / administration & dosage
  • Warfarin / adverse effects*

Substances

  • Anticoagulants
  • Warfarin