Withanolides from Jaborosa caulescens var. bipinnatifida

Phytochemistry. 2014 Feb:98:232-5. doi: 10.1016/j.phytochem.2013.11.005. Epub 2013 Dec 5.

Abstract

Withanolides 2,3-dihydrotrechonolide A (1) and 2,3-dihydro-21-hydroxytrechonolide A (2) were isolated along with two known withanolides trechonolide A (3) and jaborosalactone 39 (4) from Jaborosa caulescens var. bipinnatifida (Solanaceae). The structures of 1-2 were elucidated through 2D NMR and other spectroscopic techniques. In addition, the structure of withanolide 1 was confirmed by X-ray crystallographic analysis.

Keywords: 2,3-Dihydro-21-hydroxytrechonolide A; 2,3-Dihydrotrechonolide A; Jaborosa caulescens var. bipinnatifida; Solanaceae; Withanolide.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Crystallography, X-Ray
  • Magnetic Resonance Spectroscopy
  • Models, Molecular
  • Molecular Conformation
  • Solanaceae / chemistry*
  • Withanolides / chemistry
  • Withanolides / isolation & purification*

Substances

  • Withanolides