FLT3-ITD confers poor prognosis in patients with acute promyelocytic leukemia treated with AIDA protocols: long-term follow-up analysis

Haematologica. 2013 Dec;98(12):e161-3. doi: 10.3324/haematol.2013.095380.
No abstract available

Keywords: FLT3; acute promyelocytic leukemia; internal tandem duplication; poor prognosis.

Publication types

  • Letter

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Follow-Up Studies
  • Humans
  • Idarubicin / therapeutic use
  • Leukemia, Promyelocytic, Acute / diagnosis*
  • Leukemia, Promyelocytic, Acute / drug therapy
  • Leukemia, Promyelocytic, Acute / genetics*
  • Prognosis
  • Prospective Studies
  • Tandem Repeat Sequences / genetics*
  • Time Factors
  • Treatment Outcome
  • Tretinoin / therapeutic use
  • fms-Like Tyrosine Kinase 3 / genetics*

Substances

  • Tretinoin
  • FLT3 protein, human
  • fms-Like Tyrosine Kinase 3
  • Idarubicin

Supplementary concepts

  • AIDA protocol