Rubella virus genotype 1G and echovirus 9 as etiologic agents of exanthematous diseases in Brazil: insights from phylogenetic analysis

Arch Virol. 2014 Jun;159(6):1445-51. doi: 10.1007/s00705-013-1935-9. Epub 2013 Dec 11.

Abstract

The aim of the present study was to identify the rubella virus (RV) and enterovirus (EV) genotypes detected during the Epidemiological Surveillance on Exanthematic Febrile Diseases (VIGIFEX) study and to perform phylogenetic analysis. Ten RV- and four EV-positive oropharyngeal samples isolated from cell culture were subjected to RT-PCR and sequencing. Genotype 1G and echovirus 9 (E-9) was identified in RV- and EV-positive samples, respectively. The RV 1G genotype has been persisting in Brazil since 2000-2001. No evidence of E-9 being involved in exanthematic illness in Brazil has been reported previously. Differential laboratory diagnosis is essential for management of rash and fever disease.

MeSH terms

  • Brazil / epidemiology
  • Cluster Analysis
  • Echovirus 9 / classification
  • Echovirus 9 / genetics
  • Echovirus 9 / isolation & purification*
  • Echovirus Infections / epidemiology*
  • Echovirus Infections / virology
  • Genotype
  • Molecular Epidemiology
  • Molecular Sequence Data
  • Oropharynx / virology
  • Phylogeny
  • RNA, Viral / genetics
  • Reverse Transcriptase Polymerase Chain Reaction
  • Rubella / epidemiology*
  • Rubella / virology
  • Rubella virus / classification
  • Rubella virus / genetics
  • Rubella virus / isolation & purification*
  • Sequence Analysis, DNA

Substances

  • RNA, Viral

Associated data

  • GENBANK/KC962550
  • GENBANK/KC962551
  • GENBANK/KC962552
  • GENBANK/KC962553
  • GENBANK/KC962554
  • GENBANK/KC962555
  • GENBANK/KC962556
  • GENBANK/KC962557
  • GENBANK/KC962558
  • GENBANK/KC962559